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Joseph S Pagano Selected Research

Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)

7/2019Inhibition of UCH-L1 Deubiquitinating Activity with Two Forms of LDN-57444 Has Anti-Invasive Effects in Metastatic Carcinoma Cells.
3/2016UCH-L1 in DLBCL: marker or target?
1/2014KSHV LANA and EBV LMP1 induce the expression of UCH-L1 following viral transformation.
7/2011PU.1-dependent regulation of UCH L1 expression in B-lymphoma cells.
6/2009Positive reciprocal regulation of ubiquitin C-terminal hydrolase L1 and beta-catenin/TCF signaling.

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Joseph S Pagano Research Topics

Disease

20Neoplasms (Cancer)
01/2022 - 11/2002
10Epstein-Barr Virus Infections
01/2020 - 09/2003
7Lymphoma (Lymphomas)
01/2022 - 12/2003
6Virus Diseases (Viral Diseases)
10/2015 - 12/2003
6Neoplasm Metastasis (Metastasis)
03/2013 - 05/2003
5Nasopharyngeal Carcinoma
03/2013 - 06/2005
4Infections
01/2020 - 04/2005
3Carcinoma (Carcinomatosis)
07/2019 - 12/2003
2Acquired Immunodeficiency Syndrome (AIDS)
01/2022 - 11/2007
2Carcinogenesis
01/2019 - 08/2009
2Nasopharyngeal Neoplasms (Cancer of the Nasopharynx)
09/2017 - 03/2013
2Hypoxia (Hypoxemia)
10/2006 - 06/2004
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/2019
1Squamous Cell Carcinoma of Head and Neck
07/2019
1Infectious Mononucleosis (Glandular Fever)
10/2017
1Lymphatic Metastasis
09/2017
1B-Cell Lymphoma (Lymphoma, B Cell)
03/2016
1Hepatocellular Carcinoma (Hepatoma)
06/2007
1Burkitt Lymphoma (Burkitt's Lymphoma)
12/2005
1Hairy Leukoplakia
08/2005
1Latent Infection
04/2004

Drug/Important Bio-Agent (IBA)

10Membrane Proteins (Integral Membrane Proteins)IBA
07/2019 - 11/2002
9Proteins (Proteins, Gene)FDA Link
01/2019 - 09/2003
7Oncogene Proteins (Oncogene Protein)IBA
11/2011 - 11/2002
5Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)IBA
07/2019 - 06/2009
5UbiquitinIBA
03/2016 - 12/2005
4Antiviral Agents (Antivirals)IBA
06/2018 - 04/2005
4Interferon Regulatory Factor-7 (Interferon Regulatory Factor 7)IBA
09/2017 - 09/2003
4Epstein-Barr virus EBV-associated membrane antigenIBA
09/2017 - 06/2005
3EnzymesIBA
01/2019 - 05/2003
2Viral DNAIBA
10/2017 - 09/2005
2RNA (Ribonucleic Acid)IBA
06/2010 - 12/2005
2Biological ProductsIBA
08/2009 - 06/2007
2Hypoxia-Inducible Factor 1IBA
10/2006 - 06/2004
2beta CateninIBA
12/2005 - 12/2003
2InterferonsIBA
08/2005 - 04/2005
1Deubiquitinating EnzymesIBA
01/2020
1LDN 57444IBA
07/2019
1DNA (Deoxyribonucleic Acid)IBA
11/2018
1Formaldehyde (Formol)FDA Link
11/2018
1ParaffinIBA
11/2018
1Viral ProteinsIBA
07/2014
1latency-associated nuclear antigenIBA
01/2014
1Carrier Proteins (Binding Protein)IBA
03/2013
1ChromatinIBA
03/2013
1cytidylyl-(3'-5')-cytidine (CpC)IBA
11/2011
1Pharmaceutical PreparationsIBA
12/2009
1Phosphotransferases (Kinase)IBA
01/2008
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2008
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
10/2007
1Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
10/2007
1Glycoproteins (Glycoprotein)IBA
02/2007
1A-factor (Streptomyces)IBA
02/2007
1Mucin-1 (CA 15-3 Antigen)IBA
02/2007
1Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
10/2006
1Ligases (Synthetase)IBA
12/2005
1Glycogen Synthase KinasesIBA
12/2005
1Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
09/2005
1Cidofovir (Vistide)FDA Link
09/2005
1maribavirIBA
08/2005
1Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
06/2005
1GuanineIBA
06/2005
1CREB-Binding ProteinIBA
04/2005
1Basic Helix-Loop-Helix Transcription FactorsIBA
06/2004
1ElementsIBA
06/2004
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2004
1Tyrosine (L-Tyrosine)FDA Link
05/2004
1Epstein-Barr Virus Nuclear AntigensIBA
04/2004
1Interferon-alpha (Interferon Alfa)IBA
02/2004
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2003

Therapy/Procedure

2Therapeutics
01/2020 - 11/2007
1Art Therapy
01/2022